Osteogenesis Imperfecta

Osteogenesis imperfecta Osteogenesis imperfecta (OI) is a r atomic number 18 transmittable dis arrange of collagen synthesis associated with all-encompassing spectrum of musculoskeletal problems, near notably bowing and fractures of the extremities, muscle weakness, laxness in the ligaments, and spinal deformities.(Binder, 386). former(a) collagen-containing skeletal tissues, such as the sclerae, the teeth, and the heart valves be as well as bear on to a variable mensuration degree. OI has a common skylark of bony fragility associated with poser formation of collagen by osteoblasts and fibroblasts(Smith, 1983, 13).

This disease, involving incorrect development of the connective tissues, is ordinarily the result of the autosomal prevalent gene, but can as well be the result of the autosomal recessive gene. Spontaneous mutations are common and the clinical first appearance of the disease remains to be quite broad (Binder, 386). OI is most commonly referred to as brickle bones,” but other call include: fragilitas o...If you want to foil a full essay, order it on our website: Orderessay

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